You are using an outdated browser, please update your browser to get the best experience on this website.

Update Now

Drug Interactions

Pharmacokinetic

A standard drug dose assumes normal clearances. If clearance is altered in a drug interaction, the steady state concentration will change.

An enzyme inducer will increase the clearance, by providing more enzyme. Drug concentrations will decrease.

An enzyme inhibitor will decrease the clearance by making less enzyme available. Drug concentration will increase.

Toggle the inducer/inhibitor buttons, and make dose corrections using the slider.

0

Concentration

minimum toxic concentration

minimum effective concentration

Time

Low High
Induction
Inhibition