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The Half-Life

Summary

The shape of the Cp-time curve depends on the Vd, Cl, t1/2, dose size and dose interval.

Manipulate any of the sliders, to see various combinations that allow you to keep the Cp-time curve within the therapeutic window.

Dose 1 Dose 2 Dose 3 Dose 4 Dose 5 Dose 6 Dose 7

long

short

Cp

time (hrs)

minimum toxic concentration

minimum effective concentration

t

1/2

Small Large
Small Large
Low High
Low High