Drugs in Pregnancy
Effects of Drugs on Pregnancy
In the first 4 weeks, prior to implantation, drug exposure is relatively safe as the foetus is not exposed to the mother's blood supply. An adverse effect at this time is likely to result in spontaneous abortion (all or nothing effect).
Post-partum, drugs with a long half-life may continue to affect the baby. Drugs with a short half-life may result in neonatal withdrawal symptoms. After implantation, foetal drug concentrations are similar to those in the mother. Adverse effects depend on both drug toxicity and the developmental stage of the foetus. Adjust slider and observe the major effects.